Journal of the European Society for Gynaecological Endoscopy


Hysteroscopic Treatment of Primary Endometrial Marginal Zone B-cell Lymphoma (MALToma)

F. Scrimin 1, G. Magoga 2, G. Di Lorenzo 1, F. Romano 1, M.C. De Angelis 3, A. Vitagliano 4, J. Crugno 5, A. Di Spiezio Sardo 3

1 Institute for Maternal and Child Health, IRCCS “Burlo Garofolo”, Trieste, Italy;
2 Istituto di Ginecologia e Obstetricia, Università Cattolica del Sacro Cuore, Rome, Italy;
3 Department of Public Health, School of Medicine, University of Naples Federico II, Naples, Italy;
4 Department of Women and Children’s Health, Unit of Gynecology and Obstetrics, University of Padua, Padua, 35128, Italy;
5 Obstetrics, Gynecology and Reproductive Sciences Department. University of Miami. Miller School of Medicine. Miami, FL USA..


hysteroscopy, MALT, primary extranodal marginal zone B-cell lymphoma, polyp

Published online: Jan 24 2020


Primary extranodal marginal zone B-cell lymphomas (MALToma) of the endometrium are rare tumors. We report a case of MALToma diagnosed within an endometrial polyp in a patient presenting with postmenopausal vaginal bleeding. The patient underwent a conventional hysteroscopic procedure for intrauterine polyps. There was no suspicion of malignancy during the preoperative investigations or at surgery. Conventional bipolar resection of the polyps was performed. The present case demonstrates that conservative management of endometrial MALToma may be considered as a safe alternative to hysterectomy. Further data on long-term follow up is needed to confirm the safety of this conservative approach.