Journal of the European Society for Gynaecological Endoscopy


Non-invasive methods for embryo selection

H.N. Sallam1,2, N.H. Sallam2, S.H. Sallam2

1Department of Obstetrics and Gynaecology, the University of Alexandria in Egypt.

2Alexandria Fertility Center, Alexandria, Egypt.

Correspondence at:


Embryo selection, non-invasive, metabolomics, sHLA-G, oxidative stress, morpho-kinetics, time lapse monitoring

Published online: Jun 30 2016


With the widespread use of assisted reproduction, a simple and practical method for embryo selection is needed to optimize the chances of pregnancy while diminishing the incidence of multiple pregnancy and its accompanying problems. Many non-invasive methods for embryo selection have been proposed and some are more promising than others. This review summarizes these methods and attempts to evaluate them in the light of the best currently available evidence and to find out whether any of them is ripe for replacing or supplementing the time-honored method of morphological assessment.